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What are the types of lymphoma?

There are two main types of lymphoma: Hodgkin and non-Hodgkin lymphoma within which various subtypes are classified. Dr. Thomas Hodgkin, a pathologist in the 1800s, identified these cancerous cells and named them which is now called Hodgkin’s lymphoma. Patients with lymphoma Hodgkin have large cancerous cells caked as Reed-Sternberg (RS) cells. NHL patient does not have such cells.

Types of Hodgkin’s Lymphoma

There are different types of Hodgkin lymphoma. It is important to know the type because this may affect the cancer treatment.

What is Lymphocyte-depleted Hodgkin’s disease?
This is a rare, aggressive form of lymphoma occurring in around 1% of cases of lymphoma and is most frequently diagnosed in people in their 30s. Physicians can see natural lymphocytes in diagnostic tests with an excess of Reed-Sternberg cells.

What is Lymphocyte-rich Hodgkin’s disease?
This type of lymphoma is more common in men and constitutes about 5% of all cases of Hodgkin’s lymphoma. This disease is diagnosed at an early stage with the presence of and lymphocytes and Reed-Sternberg cells in diagnostic tests.

What is Mixed cellularity Hodgkin’s lymphoma?
Mixed cellularity Hodgkin’s lymphoma also contains both lymphocytes and Reed-Sternberg cells. It is more common and almost account for a quarter of Hodgkin’s lymphoma cases. It is more prevalent in older adult men.

What is Nodular lymphocyte-predominant Hodgkin’s disease?
Nodular lymphocyte-predominant Hodgkin’s disease (NLPHL) is a type of Hodgkin’s lymphoma accounting in about 5% of lymphoma patients. It is characterized by the absence of Reed-Sternberg cells. NLPHL is most common in individuals between the 30-50 years of age and it is more common in males. Rarely, this can progress or transform into aggressive NHL type.
What is Nodular sclerosis Hodgkin’s lymphoma?
This is on the most common type of lymphoma occurring in 70% of Hodgkin ‘s cases. It is more common in younger people than in any other group. This type of lymphoma occurs in lymph nodes where scar tissue or sclerosis is present. Fortunately, this form of lymphoma is highly treatable with high cure rate.

Types of Non Hodgkin’s Lymphoma

Non-Hodgkin’s Lymphoma (NHL) types depend on the cells that are affected and whether they are fast or slow-growing. NHL can be formed in either B-cells or T-cells of the immune system.

What is B-cell lymphoma?
The most aggressive type of NHL is diffuse large B-cell lymphoma (DLBCL). This fast-growing lymphoma originates in the blood from abnormal B cells. It can be cured if treated but it can lead to death if left untreated. The DLBCL stage aids in determining your prognosis.

What is Monoclonal Gammopathy of Undetermined Significance (MGUS)?
This condition can lead to active myeloma. This involves abnormal antibodies called M proteins that myeloma cells produce. Yet, MGUS does not cause any myeloma symptoms. Only 1 in 5 people who have been living with this disease for 20 years get active myeloma. People with MGUS are typically not treated unless they have side effects in their hands, feet, or legs such as pain and numbness, muscle weakness, bleeding, or heart or kidney problems.

What is T-cell lymphoma?
There are many types of T-cell lymphoma and is not as severe as B-cell lymphoma. This type accounts for only 15% of all NHL cases.

What is Follicular lymphoma?
This type of NHL starts in the white blood cells and is most common in older people. This lymphoma also grows slowly making the treatment get delayed.

What is Mantle cell lymphoma?
This is the aggressive and rare type of lymphoma constituting about 6% of all NHL cases. Mantel cell lymphoma involves gastrointestinal tract or bone marrow and is more commonly diagnosed at a later stage.

What is Primary mediastinal B cell lymphoma?
The B-cell lymphoma subtype accounts for nearly 10% of cases of DLBCL. It affects predominantly women in their 20s and 30s.

What is Small lymphocytic lymphoma?
Small lymphoma (SLL) is a type of lymphoma that has a slow growth rate. SLL cancer cells are mostly found in the lymph nodes. This type is identical to chronic lymphocytic leukemia (CLL), but the majority of cancer cells in the blood and bone marrow are found with CLL.

What is Lymphoplasmacytic lymphoma?
Lymphoplasmacytic lymphoma (LPL) is a rare type affecting only 1-2% of all lymphomas. It affects mostly the older adults. A subtype of LPL is Waldenstrom macroglobulinemia. It causes the abnormal production of antibodies.

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