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Types

Bone Marrow Transplant

Types

Bone Marrow Transplant

AOI > Centres of Excellence > Bone Marrow Transplant > Types

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    Types of bone marrow transplant

    Autologous (Self-Donated)

    During this type of bone marrow transplant, the bone marrow or stem cells are harvested from the patient’s own body and frozen for future use.

    Allogeneic Bone Marrow Transplant

    During this type of transplant, the bone marrow or stem cells are harvested from a donor’s body. The bone marrow transplant donor, in this case, could be a sibling/relative or an unrelated donor whose bone marrow matches with the patient’s bone marrow. It must be an HLA (Histocompatible Leukocyte antigen) match.

    Allogeneic (Donor) Transplants Using Matched Sibling

    The bone marrow during this procedure comes from the sibling of the patient, whose HLA (Histocompatible Leukocyte antigen) matches completely with the patient.

    Allogeneic Transplants Using Unrelated Donors

    The bone marrow or stem cells in this case come from the unrelated donor whose HLA (Histocompatible Leukocyte antigen) matches completely with the patient.

    Allogeneic Transplants Using Haploidentical (Half-Matched) Donors

    The bone marrow or stem cells comes from HLA (Histocompatible Leukocyte antigen) half-matched donors who could be biological parents of the patient or half-matched siblings.

    Allogeneic Transplants Using Umbilical Cord Blood

    Umbilical cord blood cells collected from a newborn baby right after the birth is a rich source of stem cells. These stem cells are very immature, hence the need for perfect matching is eliminated. After collecting, these cells are stored and frozen until they are used for a transplant.

    Reduced-Intensity Conditioning Allogeneic Transplants

    Also called as mini-transplant, this bone marrow transplant procedure uses lower, less toxic doses of chemotherapy and radiation than what is normally given before standard allogeneic transplantations.
    This type of transplant is well-suited for patients who are older and have organ complications or who are otherwise not healthy to undergo standard allogeneic transplantation.

    Peripheral Blood Stem Cells (PBSC)

    The same blood-forming cells that are found in bone marrow are also found in the circulating (peripheral) blood and therefore, PBSC donation is often considered as an option during a bone marrow transplant procedure. PBSC donation is a non-surgical procedure.

    Umbilical Cord Blood

    Umbilical cord blood from a new born is considered to be a rich source of stem cells.

    Donated cord blood that meets requirements is frozen and stored at a cord blood bank until used. For certain patients option of using cord blood stem cell transplants works better than transplants with marrow or peripheral blood stem cells (PBSCs).

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