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Musculoskeletal Oncology

Providing comprehensive diagnosis and treatment for benign and malignant tumors of bones and soft tissues.

Musculoskeletal Oncology

Providing comprehensive diagnosis and treatment for benign and malignant tumors of bones and soft tissues.

AOI > Centres of Excellence > Musculoskeletal Oncology > Overview

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    About AOI

    American Oncology Institute (AOI) is one of the best hospitals for musculoskeletal cancer treatment in India or orthopaedic cancer centre in India providing extensive cancer care in its centres all over India. At American Oncology Institute, we provide first-string quality diagnostic services and high-class standards of treatments.

    At AOI, with our team of eminently skilled bone cancer specialists in India as well as top musculoskeletal cancer specialists in we strive to provide modern healthcare facilities for a standard bone & soft tissue cancer treatment in India as well as bone cancer operation in Hyderabad.

    Apart from premium cancer care, we understand the needs of the patients and provide them a relaxed and comfortable environment.

    What is Musculoskeletal Oncology?

    Musculoskeletal oncology (or orthopaedic oncology), sub-branch of orthopaedic oncology, involves the diagnosis and treatment of various types of bone and soft tissue cancers. Musculoskeletal oncology deals with the diagnosis and treatment of children and adults with bone and soft tissue cancers. These cancers can develop in any part of the body that involves a bone including in the hands, arms, elbows, shoulders, scapula, feet, knees, thighs, hips, pelvis, or the sacrum. The treatment for musculoskeletal malignancies has changed dramatically in the past few years.

    How musculoskeletal oncology can help in treatment of bone and soft tissue cancers?

    Musculoskeletal oncology is a sub-specialty of orthopedic oncology, and it involves the diagnosis of bone cancer, diagnosis and treatment of benign and malignant tumors, as well as other pathologically abnormal lesions of the musculoskeletal system in adults and children. Bone and soft tissue tumors comprise of around 0.2% of all tumors and are relatively rare. The most common tumors in this subset are osteosarcoma (OGS), chondrosarcoma, and Ewing sarcoma.

    Cancer from one organ/region of the body may spread (metastasis) to other body parts through the blood or lymphatic circulation and can involve the skeletal system (bones and muscles). This is usually seen in cases of advanced or stage IV breast cancer, lung cancer, etc. Metastatic tumors involving the bone result in pathological fractures, pain, and high than normal levels of calcium in the blood. This stage requires orthopedic intervention with regards to the management of the orthopedic conditions happened either due to tumor metastasis and/or orthopedic tumor to provide a better recovery and treatment outcome to the patient. Previously, these cancer related-orthopedic conditions were less often treated and operated apart from the amputation of that body part. But with the advancement of oncology and medical science, there are many advanced options available for the management of cancer-related orthopedic conditions, including benign, malignant and metastatic diseases of the musculoskeletal system.

    The orthopedic oncologist or orthopedic cancer specialist along with the medical oncologist, radiation oncologist, radiologist, and pathologist together create an individualized treatment plan for cancer treatment while ensuring better clinical outcomes and good quality of life for patients.

    Who all are involved in the treatment of bone and soft tissue tumors?

    Musculoskeletal oncology or orthopedic oncology plays an important role in treating bone and soft tissue tumors in children and adults as well as cancer-related orthopedic conditions. Bone and soft tissue cancer treatment as well as management requires a multidisciplinary approach with a combined involvement of an orthopedic oncologist, medical oncologist, radiation oncologist, radiologists, and pathologist.

    What are the common symptoms of bone cancer?

    Usually the symptoms of bone and soft tissue cancers go unnoticed since they are not very common.

    Whenever symptomatic, the patient may have:

    • Pain and/or swelling in the affected muscle or bone
    • Any kind of lump or mass in the affected area (most common)
    • Unusual fractures without any causative factor or very minor injury

    For any such symptoms, it is always better to consult a doctor.

    Why is early diagnosis important in bone cancer?

    Bone cancer can affect anyone of any age group and since there is no exact known cause of bone cancer, there are no specific precautionary measures to follow. Therefore, its early detection and correct diagnosis is really important.

    What are the types of musculoskeletal cancers or bone and soft tissue cancers or orthopaedic tumors?

    Bone and soft tissue cancers are of following types:

    Primary bone tumor

    Primary bone cancers fall under the category of cancers called sarcomas. Soft-tissue sarcomas are kind of sarcomas that originate in muscle, fat, blood vessels, or other supporting tissue of the body. However, sometimes, tumors develop in the bones first and are therefore called primary bone tumors. They can be either benign (no cancerous cells) or malignant (cancerous). Primary bone sarcomas comprise approximately 0.2% of all cancers. The common types are:

    • Multiple Myeloma
      Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.
    • Osteosarcoma
      Osteosarcoma is a type of cancer in which tumor cells produce immature bone known as osteoid. Although osteosarcoma is rare, it is the most common childhood bone cancer.
    • Chondrosarcoma
      Chondrosarcoma is a cancer composed of cells derived from transformed cells that produce cartilage. About 30% of skeletal system cancers are chondrosarcomas.
    • Ewing’s sarcoma
      Ewing’s sarcoma is a very rare type of cancerous tumor that grows in your bones or the soft tissue around your bones, such as cartilage or the nerves.

    Secondary bone tumor or Metastatic tumors

    Soft tissue tumors that metastasize (spread) to the bones are called secondary bone tumors. Secondary bone tumors are always malignant. They commonly originate in the breast, kidney, lung, prostate, and thyroid.

    How are bone and soft tissue tumors diagnosed?

    • Medical history – Like all other cancers, a complete medical history is sought; any existing or past health issues, early symptoms & current symptoms are reviewed; familial history of bone cancer is checked; and history of smoking is checked.
    • Imaging and scans – X-Ray, CT scan / Computed Tomography, MRI, and Bone Scan / PET scan are conducted.
    • Biopsy – To determine the type of tumor biopsy sample is also done; needle biopsy is preferred rather than conventional open biopsies as it decreases the continuation of surrounding tissue with tumor cells, thereby facilitating limb salvage surgery for malignant bone tumors. Needle biopsy is done as outpatient modality under local anesthesia with minimal contamination of surrounding tissue/structures.
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