Age: Teenagers and growing children with growth spurts are at increased risk for osteosarcoma.
Gender: Males are at increased risk for osteosarcoma compared to females.
Height: Kids with more height are at greater risk than kids with shorter height.
Radiation exposure: Exposure to high-dose radiation for treating other cancers increases the risk of osteosarcoma.
Underlying medical conditions: Several underlying medical conditions increase the risk of osteosarcoma. These are Paget’s disease of the bone, Rothmund-Thomson syndrome, Li-Fraumeni syndrome, Werner syndrome, Bloom syndrome, Diamond-Blackfan anemia, or hereditary retinoblastoma.
Bone infarction: Bone infarction occurs when the vessels supplying the blood to the bones get blocked or damaged, resulting in the death of bone cells. Bone infarction increases the risk of osteosarcoma.
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